Observations on the Structure, Development and Electrical Reactions of the Internal Ear of the Shaker-1 Mouse (Mus musculus)

Abstract

A comparative study has been made of the embryology, anatomy and electrical reactions of the cochlea in the normal and shaker-1 mouse between the ages of 9 hours and 329 days. Cochlear degeneration in the latter is initiated after birth in a fully formed organ, and is associated with marked changes in its electrical reactions.